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1.
Appl Math Model ; 121: 506-523, 2023 Sep.
Article in English | MEDLINE | ID: covidwho-2313873

ABSTRACT

A new contagious disease or unidentified COVID-19 variants could provoke a new collapse in the global economy. Under such conditions, companies, factories, and organizations must adopt reopening policies that allow their operations to reduce economic effects. Effective reopening policies should be designed using mathematical models that emulate infection chains through individual interactions. In contrast to other modeling approaches, agent-based schemes represent a computational paradigm used to characterize the person-to-person interactions of individuals inside a system, providing accurate simulation results. To evaluate the optimal conditions for a reopening policy, authorities and decision-makers need to conduct an extensive number of simulations manually, with a high possibility of losing information and important details. For this reason, the integration of optimization and simulation of reopening policies could automatically find the realistic scenario under which the lowest risk of infection was attained. In this paper, the metaheuristic technique of the Whale Optimization Algorithm is used to find the solution with the minimal transmission risk produced by an agent-based model that emulates a hypothetical re-opening context. Our scheme finds the optimal results of different generical activation scenarios. The experimental results indicate that our approach delivers practical knowledge and essential estimations for identifying optimal re-opening strategies with the lowest transmission risk.

2.
Comput Biol Med ; 148: 105847, 2022 09.
Article in English | MEDLINE | ID: covidwho-1936227

ABSTRACT

The global pandemic caused by the coronavirus (COVID-19) disease has collapsed the worldwide economy. Elements such as non-obligatory vaccination, new strain variants and lack of discipline to follow social distancing measures suggest the possibility that COVID-19 may continue to exist, exhibiting the behavior of a seasonal disease. As the socio-economic crisis has become unsustainable, all countries are planning strategies to gradually restart their economic and social activities. Initially, several containment measures have been adopted involving social distancing, infection detection tests, and ventilation systems. Despite the implementation of such policies, there exists a lack of evaluation of their performance to reduce the contagion index. This means there are no appropriate indicators to decide which intervention or set of interventions present the most effective result. Under these conditions, the development of models that provide useful information in the design and evaluation of containment measures and re-opening policies is of prime concern. In this paper, a novel approach to model the transmission process of COVID-19 in closed environments is proposed. The proposed model can simulate the effects that result from the complex interaction among individuals when they follow a particular containment measure or re-opening policy. With the proposed model, different hypothetical re-opening policies, that are otherwise impossible to analyze in real conditions, can be tested. Computer experiments demonstrate that the proposed model provides suitable information and realistic predictions, which are appropriate for designing strategies that allow a safe return to economic activities.


Subject(s)
COVID-19 , Humans , Pandemics , Policy , SARS-CoV-2
3.
Expert Syst Appl ; 193: 116377, 2022 May 01.
Article in English | MEDLINE | ID: covidwho-1587805

ABSTRACT

Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It may cause serious ailments in infected individuals and complications may lead to death. X-rays and Computed Tomography (CT) scans can be used for the diagnosis of the disease. In this context, various methods have been proposed for the detection of COVID-19 from radiological images. In this work, we propose an end-to-end framework consisting of deep feature extraction followed by feature selection (FS) for the detection of COVID-19 from CT scan images. For feature extraction, we utilize three deep learning based Convolutional Neural Networks (CNNs). For FS, we use a meta-heuristic optimization algorithm, Harmony Search (HS), combined with a local search method, Adaptive ß -Hill Climbing (A ß HC) for better performance. We evaluate the proposed approach on the SARS-COV-2 CT-Scan Dataset consisting of 2482 CT scan images and an updated version of the previous dataset containing 2926 CT scan images. For comparison, we use a few state-of-the-art optimization algorithms. The best accuracy scores obtained by the present approach are 97.30% and 98.87% respectively on the said datasets, which are better than many of the algorithms used for comparison. The performances are also at par with some recent works which use the same datasets. The codes for the FS algorithms are available at: https://github.com/khalid0007/Metaheuristic-Algorithms.

4.
Appl Soft Comput ; 111: 107698, 2021 Nov.
Article in English | MEDLINE | ID: covidwho-1309154

ABSTRACT

Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It may cause severe ailments in infected individuals. The more severe cases may lead to death. Automated methods which can detect COVID-19 in radiological images can help in the screening of patients. In this work, a two-stage pipeline composed of feature extraction followed by feature selection (FS) for the detection of COVID-19 from CT scan images is proposed. For feature extraction, a state-of-the-art Convolutional Neural Network (CNN) model based on the DenseNet architecture is utilised. To eliminate the non-informative and redundant features, the meta-heuristic called Harris Hawks optimisation (HHO) algorithm combined with Simulated Annealing (SA) and Chaotic initialisation is employed. The proposed approach is evaluated on the SARS-COV-2 CT-Scan dataset which consists of 2482 CT-scans. Without the Chaotic initialisation and the SA, the method gives an accuracy of around 98.42% which further increases to 98.85% on the inclusion of the two and thus delivers better performance than many state-of-the-art methods and various meta-heuristic based FS algorithms. Also, comparison has been drawn with many hybrid variants of meta-heuristic algorithms. Although HHO falls behind a few of the hybrid variants, when Chaotic initialisation and SA are incorporated into it, the proposed algorithm performs better than any other algorithm with which comparison has been drawn. The proposed algorithm decreases the number of features selected by around 75% , which is better than most of the other algorithms.

5.
Comput Biol Med ; 121: 103827, 2020 06.
Article in English | MEDLINE | ID: covidwho-380456

ABSTRACT

The rapid spread of the coronavirus disease (COVID-19) has become a global threat affecting almost all countries in the world. As countries reach the infection peak, it is planned to return to a new normal under different coexistence conditions in order to reduce the economic effects produced by the total or partial closure of companies, universities, shops, etc. Under such circumstances, the use of mathematical models to evaluate the transmission risk of COVID-19 in various facilities represents an important tool in assisting authorities to make informed decisions. On the other hand, agent-based modeling is a relatively new approach to model complex systems composed of agents whose behavior is described using simple rules. Different from classical mathematical models (which consider a homogenous population), agent-based approaches model individuals with distinct characteristics and provide more realistic results. In this paper, an agent-based model to evaluate the COVID-19 transmission risks in facilities is presented. The proposed scheme has been designed to simulate the spatiotemporal transmission process. In the model, simulated agents make decisions depending on the programmed rules. Such rules correspond to spatial patterns and infection conditions under which agents interact to characterize the transmission process. The model also includes an individual profile for each agent, which defines its main social characteristics and health conditions used during its interactions. In general, this profile partially determines the behavior of the agent during its interactions with other individuals. Several hypothetical scenarios have been considered to show the performance of the proposed model. Experimental results have demonstrated that the simulations provide useful information to produce strategies for reducing the transmission risks of COVID-19 within the facilities.


Subject(s)
Betacoronavirus , Coronavirus Infections/transmission , Pneumonia, Viral/transmission , Systems Analysis , COVID-19 , Computational Biology , Computer Simulation , Coronavirus Infections/epidemiology , Disease Susceptibility/epidemiology , Health Behavior , Health Facilities , Humans , Models, Biological , Pandemics/statistics & numerical data , Pneumonia, Viral/epidemiology , Population Dynamics/statistics & numerical data , SARS-CoV-2
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